Non-compartment model to compartment model pharmacokinetics transformation meta-analysis – a multivariate nonlinear mixed model
نویسندگان
چکیده
منابع مشابه
COMKAT: compartment model kinetic analysis tool.
UNLABELLED Compartment models are the basis for most physiologically based quantification of nuclear medicine data. Although some software packages are available for this purpose, many are expensive, run on relatively few types of computers or are of limited capability, and cannot be extended because of the unavailability of source code. Consequently, institutions with modeling expertise often ...
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A two-compartment neuronal model is investigated. The model neuron is composed of two interconnected parts – a dendrite and a trigger zone, with a white noise input in the dendritic compartment. The first and the second moments of the stochastic processes describing the membrane depolarization in both compartments are derived and investigated. When a firing threshold is not imposed, the level o...
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Adrienn Csiszkó 1, Klaudia Balog 1, Zoltán Attila Godó 2, Gyula Juhász 2, Katalin Pető 3, Ádám 5 Deák 3, Mariann Berhés 4, Norbert Németh 3, Zsolt Bodnár 5 * and Zsolt Szentkereszty 1 6 1 University of Debrecen, Faculty of Medicine, Institute of Surgery; [email protected] 7 2 University of Debrecen, Faculty of Informatics, Department of Information Technology; 8 [email protected] 9 3 Uni...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2010
ISSN: 1752-0509
DOI: 10.1186/1752-0509-4-s1-s8